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1. Zetterberg
H, Campbell WA, Yang HW, Xia W. The cytosolic
loop of the g-secretase component
presenilin enhancer 2 (Pen-2) protects zebrafish embryos from
apoptosis. J Biol Chem. 2006, 281, 11933-9.
2. Campbell WA, Yang H, Zetterberg H, Baulac S,
Sears JA, Liu T, Wong STC, Zhong TP, Xia W. Zebrafish lacking Alzheimer presenilin enhancer
2 (Pen-2) demonstrate excessive p53 dependent apoptosis and neuronal
loss. J Neurochem. 2006, 96, 1423-40.
3. Liu T, Lu, J, Wang Y, Campbell WA, Huang L, Zhu
J, Xia W, Wong STC. Computerizedimage
analysis for quantitative neuronal phenotyping in zebrafish. J
Neurosci Methods. 2006, 153, 190-202.
4. Baulac S, Lavoie M, Strahle J, Schlossmacher M,
and Xia W. Dimerization of
Parkinson disease-causing DJ-1 and formation of high molecular weight
complexes in human brain. Mol. Cell. Neurosci. 2004,
27, 236-246.
5. Zetterberg H, Blennow
K, Xia W. RNA interference:
applications in research on amyloidogenesis in Alzheimer's disease.
Progress in RNA Res. 2004, in press.
6. Baulac S, Lavoie M, Kimberly W, Strahle J, Wolfe M,
Selkoe D and Xia W. Functional g-secretase
complex assembly in Golgi/trans-Golgi network: interactions among
presenilin, nicastrin, Aph1, Pen-2 and g-secretase
substrates. 2003, Neurobiol Dis., 14, 194-204.
- Campbell WA, Reed MLO, Wolfe, M, Xia W. Presenilin
Endoproteolysis Mediated by an Aspartyl Protease Activity
Pharmacologically Distinct from g-Secretase.
J
Neurochem 2003, 85, 1563-1574.
- Xia W. Amyloid Inhibitors and
Alzheimer’s Disease. Curr Opinion
Investigational Drugs. 2003, 4(1), 55-59.
- Xia W. The Relationship between Presenilinase
and g-Secretase. Drug News &
Perspectives. 2003, 16(2), 69-74. Cover.
- Xia W and Wolfe M. Intramembrane Proteolysis
by Presenilin-like Aspartyl Protease. J. Cell Sci. 2003,
116(14), 2839-2844.
- Campbell WA, Iskandar M, Reed MLO, Xia W.
Endoproteolysis of presenilin in vitro: inhibition by a g-secretase inhibitor. Biochemistry
2002, 41, 3372-3379.
- Xia W. Amyloid metabolism and secretases in
Alzheimer’s disease. Current Neurol Neurosci
Reports, 2001, 1, 422-427.
- Xia W. Role of presenilin in g-secretase cleavage of amyloid
precursor protein. Exp Gerontol., 2000, 35,
453-460.
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